Purpose/Objective: To evaluate the effectiveness of an alternative medicine health program at a public hospital in a regional part of Thailand. To find factors affecting the health program. Methodology: The study utilized a tailored questionnaire that gathered information about health knowledge and behavior of patients who attended the hospital due to their high cholesterol, blood pressure and sugar levels. The patients were interested in the program and decided to join it. The program focused on physical, mental, social and spiritual development. It provided training and education on prevention and the promotion of external use of herbal and traditional Thai medicines, demonstrating how to use them, practicing and discussing experience of declining health (due to high blood pressure, cholesterol and sugar levels) as well as use of alternative medicine after the program had finished. Hospital staff volunteered to conduct training programs and related activities when they were not on duty. F. Taylor model of evaluation was referred to and applied to the study, which used the questionnaire to measure the output of the program. Statistical methods of chi-square and t-test were used to analyze the collected data. Findings and summary: Training and demonstrating herbal and traditional Thai medicines and group activities were statistically significant to the output of the program, which will be used as empirical evidence for further research of non-communicable disease prevention and health promotion for patients. Keywords: Chronic disease management and prevention Key Messages: 1. Herbal and Thai traditional medicines were used to prevent and promote health in a public hospital in Thailand. 2. Statistic methods have been used to prove the evaluation in the study. 3. The study could be applied to other public hospitals.