"Background: The purpose of this study is to understand the characteristics of dietitians in Taiwan in terms of personality traits and the status of burnout, and to analyze the relationship between personality traits and burnout. Methods: An online questionnaire survey was developed to collect data. Three hundred twenty practicing dietitians voluntarily participated in this nationwide study. The instrument used in this study was a self-administered structured questionnaire, consisting of general information, personality traits, and burnout inventory. Descriptive statistics and multiple linear regression analysis were used for analyzing data. Results: (1) The mean scores of single item for â€œextraversionâ€, â€œagreeablenessâ€, â€œconscientiousnessâ€ and â€œopenness to experienceâ€ are higher than 3. The highest score falls on â€œconscientiousnessâ€ (4.1) while the lowest score falls on â€œneuroticismâ€ (2.7); (2) The mean score of emotional exhaustion is 25.94; (3) The five factor model of personality traits can significantly predict burnout of dietitians (F=30.293, p<.001). The five subscales of personality traits account for 39.1% of the total variance of burnout. The most powerful predictor is â€œneuroticismâ€ (Î²=0.533, t=10.882, p<.001). Conclusions: The manifest personality traits of dietitians in this sample are conscientiousness but not neuroticism. The status of burnout in this sample is in a moderate level. Those whose personality traits manifest as neuroticism maybe more often have the occurrence of burnout. It is recommended that recruiting personnel with a positive personality trait maybe helpful in preventing the occurrence of burnout in the population of dietitians. Keywords: health promotion, occupational health, mental health, research Key Messages: 1. The manifest personality traits of Taiwan dietitians were conscientiousness but not neuroticism. 2. The burnout status of Taiwan dietitians was in a moderate level. 3. Those whose personality traits manifest as neuroticism maybe more often have the occurrence of burnout. "